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  1. A 資料種別
  2. 010 東京女子医科大学雑誌
  3. 010A 論文
  4. 70巻
  5. 3号

二次性上皮小体機能亢進症患者より得られた上皮小体細胞の同種免疫原性に関する検討

http://hdl.handle.net/10470/25063
http://hdl.handle.net/10470/25063
6042d6d6-2dc1-4c85-963f-572cdc71a181
名前 / ファイル ライセンス アクション
KJ00006020145.pdf KJ00006020145.pdf (350.7 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2010-08-10
タイトル
タイトル 二次性上皮小体機能亢進症患者より得られた上皮小体細胞の同種免疫原性に関する検討
言語
言語 jpn
資源タイプ
資源タイプ journal article
別タイトル
その他のタイトル Investigation on Allogeneicity of Parathyroid Gland Cell taken from Patients with Secondary Hyperparathyroidism
著者名 辻, 和彦

× 辻, 和彦

WEKO 263484

辻, 和彦

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澤田, 登起彦

× 澤田, 登起彦

WEKO 263485

澤田, 登起彦

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渕之上, 昌平

× 渕之上, 昌平

WEKO 263486

渕之上, 昌平

Search repository
阿岸, 鉄三

× 阿岸, 鉄三

WEKO 263487

阿岸, 鉄三

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著者別名
姓名 TSUJI, Kazuhiko
著者別名
姓名 SAWADA, Tokihiko
著者別名
姓名 FUCHINOUE, Shohei
著者別名
姓名 AGISHI, Tetsuzo
出版者
出版者 東京女子医科大学学会
受付日付
ISSN
収録物識別子タイプ ISSN
収録物識別子 0040-9022
NCID
収録物識別子タイプ NCID
収録物識別子 AN00161368
書誌情報 東京女子医科大学雑誌

巻 70, 号 3, p. 67-71, 発行日 2000-03-25
著者版フラグ
抄録
内容記述タイプ Abstract
内容記述 Parathyroid hypofunction is the complication which is occasionally encountered after the surgical treatments of secondary hyperparathyroidism. Allogeneic parathyroid cell transplantation is thought to be a promising way to treat the hypofunction syndrome of parathyroid gland. In the present study, the evaluation of the allogeneicity of parathyroid gland cells was investigated. To evaluate the allogeneicity of human parathyroid cells, flow cytometry and lymphocyte proliferation test (LPT) were done. Allogeneic human peripheral blood mononuclear cells (PBMC) were cultured with PBMC, or parathyroid cells (PTC) isolated from the patients with secondary hyperparathyroidism. After 5 days of in vitro culture, allogeneic human PBMC were analyzed by flow cytometry for the phenotypic changes in CD3/CD25 double positive cells, or ^3H-thymi.dine uptake tests were done for LPT. T cells of allogeneic PBMC expressed higher level of CD25 when stimulated by PBMC rather than by PTC. ^3H-thymidine uptake was greater when stimulated by PBMC rather than by PTC. In conclusion, the allogeneicity of human parathyroid cells was less both in CD25 expression and LPT than that of PBMC.
著者所属
東京女子医科大学医学部第三外科学
著者所属
東京女子医科大学医学部第三外科学
著者所属
東京女子医科大学医学部第三外科学
著者所属
東京女子医科大学医学部第三外科学
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