{"created":"2023-06-20T16:58:51.936900+00:00","id":17764,"links":{},"metadata":{"_buckets":{"deposit":"75d56523-4dd4-4419-a149-7609ba9436b6"},"_deposit":{"created_by":3,"id":"17764","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"17764"},"status":"published"},"_oai":{"id":"oai:twinkle.repo.nii.ac.jp:00017764","sets":["140:1307:1308:1944:1946"]},"author_link":["263491","263489","263487","263486","263488","263484","263490","263485"],"item_10001_alternative_title_1":{"attribute_name":"別タイトル","attribute_value_mlt":[{"subitem_alternative_title":"Investigation on Allogeneicity of Parathyroid Gland Cell taken from Patients with Secondary Hyperparathyroidism"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-03-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"71","bibliographicPageStart":"67","bibliographicVolumeNumber":"70","bibliographic_titles":[{"bibliographic_title":"東京女子医科大学雑誌"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"辻, 和彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"澤田, 登起彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"渕之上, 昌平"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"阿岸, 鉄三"}],"nameIdentifiers":[{}]}]},"item_10001_date_25":{"attribute_name":"受付日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-08-10","subitem_date_issued_type":"Created"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Parathyroid hypofunction is the complication which is occasionally encountered after the surgical treatments of secondary hyperparathyroidism. Allogeneic parathyroid cell transplantation is thought to be a promising way to treat the hypofunction syndrome of parathyroid gland. In the present study, the evaluation of the allogeneicity of parathyroid gland cells was investigated. To evaluate the allogeneicity of human parathyroid cells, flow cytometry and lymphocyte proliferation test (LPT) were done. Allogeneic human peripheral blood mononuclear cells (PBMC) were cultured with PBMC, or parathyroid cells (PTC) isolated from the patients with secondary hyperparathyroidism. After 5 days of in vitro culture, allogeneic human PBMC were analyzed by flow cytometry for the phenotypic changes in CD3/CD25 double positive cells, or ^3H-thymi.dine uptake tests were done for LPT. T cells of allogeneic PBMC expressed higher level of CD25 when stimulated by PBMC rather than by PTC. ^3H-thymidine uptake was greater when stimulated by PBMC rather than by PTC. In conclusion, the allogeneicity of human parathyroid cells was less both in CD25 expression and LPT than that of PBMC.","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"263488","nameIdentifierScheme":"WEKO"}],"names":[{"name":"TSUJI, Kazuhiko"}]},{"nameIdentifiers":[{"nameIdentifier":"263489","nameIdentifierScheme":"WEKO"}],"names":[{"name":"SAWADA, Tokihiko"}]},{"nameIdentifiers":[{"nameIdentifier":"263490","nameIdentifierScheme":"WEKO"}],"names":[{"name":"FUCHINOUE, Shohei"}]},{"nameIdentifiers":[{"nameIdentifier":"263491","nameIdentifierScheme":"WEKO"}],"names":[{"name":"AGISHI, Tetsuzo"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東京女子医科大学学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00161368","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0040-9022","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_35":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京女子医科大学医学部第三外科学"},{"subitem_text_value":"東京女子医科大学医学部第三外科学"},{"subitem_text_value":"東京女子医科大学医学部第三外科学"},{"subitem_text_value":"東京女子医科大学医学部第三外科学"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-03-27"}],"displaytype":"detail","filename":"KJ00006020145.pdf","filesize":[{"value":"350.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006020145.pdf","url":"https://twinkle.repo.nii.ac.jp/record/17764/files/KJ00006020145.pdf"},"version_id":"aa13e877-fb6c-473e-a87a-4fca8efe7655"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"二次性上皮小体機能亢進症患者より得られた上皮小体細胞の同種免疫原性に関する検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"二次性上皮小体機能亢進症患者より得られた上皮小体細胞の同種免疫原性に関する検討"}]},"item_type_id":"10001","owner":"3","path":["1946"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-08-10"},"publish_date":"2010-08-10","publish_status":"0","recid":"17764","relation_version_is_last":true,"title":["二次性上皮小体機能亢進症患者より得られた上皮小体細胞の同種免疫原性に関する検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T22:42:04.983411+00:00"}