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  1. A 資料種別
  2. 010 東京女子医科大学雑誌
  3. 010A 論文
  4. 66巻
  5. 4号

免疫異常による神経疾患(神経-免疫-内分泌,<特集>東京女子医科大学学会第61回総会)

http://hdl.handle.net/10470/23375
http://hdl.handle.net/10470/23375
9ffcd7e3-c467-4cc4-a5f3-28e3350a0bd4
名前 / ファイル ライセンス アクション
KJ00006025570.pdf KJ00006025570.pdf (1.0 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2010-08-10
タイトル
タイトル 免疫異常による神経疾患(神経-免疫-内分泌,<特集>東京女子医科大学学会第61回総会)
言語
言語 jpn
資源タイプ
資源タイプ journal article
別タイトル
その他のタイトル Immune Abnormality in Neurological Diseases(Neuro-Immuno-Endocrinology)
著者名 太田, 宏平

× 太田, 宏平

WEKO 258671

太田, 宏平

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著者別名
姓名 OTA, Kohei
出版者
出版者 東京女子医科大学学会
受付日付
ISSN
収録物識別子タイプ ISSN
収録物識別子 0040-9022
NCID
収録物識別子タイプ NCID
収録物識別子 AN00161368
書誌情報 東京女子医科大学雑誌

巻 66, 号 4, p. 203-214, 発行日 1996-04-25
著者版フラグ
抄録
内容記述タイプ Abstract
内容記述 Multiple sclerosis (MS) is thought to be an autoimmune disease mediated by T cells respond to central nervous myelin antigens including myelin basic protein (MBP) and proteolipid protein because of their encephalitogenic potentials in experimental autoimmune encephalomyelitis, animal model of MS. We report a higher frequency of T cell lines reactive to MBP between residues 84-102 in patients with MS in both Caucasians and Japanese, so it is likely that MBP reactive T cells for this region have an important role in the etiology of patients with MS. Guillain-Barre syndrome (GBS) in which anti-glycolipid antibodies were proved in recently years is considered as another typical neuroimmunological disease however it is still examined whether anti-neuronal antibody (ANA) is a primary cause of demyelination in GBS. In addition to GBS, other specific ANAs were detected in paraneoplastic neurological syndrome such as LambertEaton myasthenic syndrome, paraneoplastic cerebellar degeneration and paraneoplastic sensory neuropathy. And investigations of such ANAs in the various neuroimmunological disorders are becoming useful diagnostic tools.
著者所属
東京女子医科大学脳神経センター神経内科
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