{"created":"2023-06-20T16:57:37.433757+00:00","id":16076,"links":{},"metadata":{"_buckets":{"deposit":"f6f56fbb-eb7c-4201-800c-f5bafe35ae1c"},"_deposit":{"created_by":3,"id":"16076","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"16076"},"status":"published"},"_oai":{"id":"oai:twinkle.repo.nii.ac.jp:00016076","sets":["140:1307:1308:1902:1905"]},"author_link":["258672","258671"],"item_10001_alternative_title_1":{"attribute_name":"別タイトル","attribute_value_mlt":[{"subitem_alternative_title":"Immune Abnormality in Neurological Diseases(Neuro-Immuno-Endocrinology)"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-04-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"214","bibliographicPageStart":"203","bibliographicVolumeNumber":"66","bibliographic_titles":[{"bibliographic_title":"東京女子医科大学雑誌"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"太田, 宏平"}],"nameIdentifiers":[{}]}]},"item_10001_date_25":{"attribute_name":"受付日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-08-10","subitem_date_issued_type":"Created"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Multiple sclerosis (MS) is thought to be an autoimmune disease mediated by T cells respond to central nervous myelin antigens including myelin basic protein (MBP) and proteolipid protein because of their encephalitogenic potentials in experimental autoimmune encephalomyelitis, animal model of MS. We report a higher frequency of T cell lines reactive to MBP between residues 84-102 in patients with MS in both Caucasians and Japanese, so it is likely that MBP reactive T cells for this region have an important role in the etiology of patients with MS. Guillain-Barre syndrome (GBS) in which anti-glycolipid antibodies were proved in recently years is considered as another typical neuroimmunological disease however it is still examined whether anti-neuronal antibody (ANA) is a primary cause of demyelination in GBS. In addition to GBS, other specific ANAs were detected in paraneoplastic neurological syndrome such as LambertEaton myasthenic syndrome, paraneoplastic cerebellar degeneration and paraneoplastic sensory neuropathy. And investigations of such ANAs in the various neuroimmunological disorders are becoming useful diagnostic tools.","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"258672","nameIdentifierScheme":"WEKO"}],"names":[{"name":"OTA, Kohei"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東京女子医科大学学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00161368","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0040-9022","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_35":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京女子医科大学脳神経センター神経内科"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-03-27"}],"displaytype":"detail","filename":"KJ00006025570.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006025570.pdf","url":"https://twinkle.repo.nii.ac.jp/record/16076/files/KJ00006025570.pdf"},"version_id":"0e36444f-9ca6-49d6-9b7f-9ebe33edbd9a"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"免疫異常による神経疾患(神経-免疫-内分泌,<特集>東京女子医科大学学会第61回総会)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"免疫異常による神経疾患(神経-免疫-内分泌,<特集>東京女子医科大学学会第61回総会)"}]},"item_type_id":"10001","owner":"3","path":["1905"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-08-10"},"publish_date":"2010-08-10","publish_status":"0","recid":"16076","relation_version_is_last":true,"title":["免疫異常による神経疾患(神経-免疫-内分泌,<特集>東京女子医科大学学会第61回総会)"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T23:18:54.415461+00:00"}