{"_buckets": {"deposit": "474f3ca8-23ec-47fe-ab8a-8d69c37773d9"}, "_deposit": {"created_by": 3, "id": "20463", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "20463"}, "status": "published"}, "_oai": {"id": "oai:twinkle.repo.nii.ac.jp:00020463", "sets": ["2031"]}, "author_link": ["298873", "298874"], "item_10001_alternative_title_1": {"attribute_name": "別タイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Neuromyelitis Optica and Autoantibodies to Aquaporin(Special Issue in Hornor of the Retirement of Professor Makoto Iwata at the Department of Neurology, Tokyo Women\u0027s Medical University)"}]}, "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2008-02-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "Extra", "bibliographicPageEnd": "E52", "bibliographicPageStart": "E42", "bibliographicVolumeNumber": "78", "bibliographic_titles": [{"bibliographic_title": "東京女子医科大学雑誌"}]}]}, "item_10001_creator_2": {"attribute_name": "著者名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "太田, 宏平"}], "nameIdentifiers": [{"nameIdentifier": "298873", "nameIdentifierScheme": "WEKO"}]}]}, "item_10001_date_25": {"attribute_name": "受付日付", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2010-08-10", "subitem_date_issued_type": "Created"}]}, "item_10001_description_34": {"attribute_name": "注記", "attribute_value_mlt": [{"subitem_description": "神経内科学教室岩田誠教授退任記念特別号", "subitem_description_type": "Other"}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Neuromyelitis optica (NMO), also known as Devic\u0027s disease, is thought to be a severe inflammatory demyelinating disease of the central nervous system (CNS) that mainly involves the optic nerve and spinal cord. Because of the clinical and pathological manifestation, NMO is considered as a severe form of multiple sclerosis (MS). Here in Japan, it is not only diagnosed as optic-spinal MS, but is often treated with an immunomodulating agent, interferon beta. In 2004, NMO-IgG or an autoantibody to aquaporin-4 of perivascular astroglia and ependymal cells of the CNS, which is a first specific marker of the demyelinating disease, was identified in the serum of NMO patients, and clearly distinguished NMO from MS. Therefore, the pathogenesis and treatment of NMO might be different from that of MS. For a reference on an advanced management of a patient with NMO, recently reported data on the clinical features and possible treatments of NMO are reviewed and summarized in this article.", "subitem_description_type": "Abstract"}]}, "item_10001_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "298874", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "OTA, Kohei"}]}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "東京女子医科大学学会"}]}, "item_10001_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00161368", "subitem_source_identifier_type": "NCID"}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0040-9022", "subitem_source_identifier_type": "ISSN"}]}, "item_10001_subject_47": {"attribute_name": "著者キーワード", "attribute_value_mlt": [{"subitem_subject": "neuromyelitis optica", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Devic\u0027s disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "multiple sclerosis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "aquaporin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "NMO-IgG", "subitem_subject_scheme": "Other"}]}, "item_10001_text_35": {"attribute_name": "著者所属", "attribute_value_mlt": [{"subitem_text_value": "東京理科大学理学部:東京女子医科大学医学部神経内科学"}]}, "item_10001_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-08-22"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00006015112.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "KJ00006015112.pdf", "url": "https://twinkle.repo.nii.ac.jp/record/20463/files/KJ00006015112.pdf"}, "version_id": "095e78a2-d5e6-47a4-8d99-e98c0904d2ae"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "視神経脊髄炎と抗アクアポリン抗体(神経内科学教室岩田誠教授退任記念特別号)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "視神経脊髄炎と抗アクアポリン抗体(神経内科学教室岩田誠教授退任記念特別号)"}]}, "item_type_id": "10001", "owner": "3", "path": ["2031"], "permalink_uri": "http://hdl.handle.net/10470/27762", "pubdate": {"attribute_name": "公開日", "attribute_value": "2010-08-10"}, "publish_date": "2010-08-10", "publish_status": "0", "recid": "20463", "relation": {}, "relation_version_is_last": true, "title": ["視神経脊髄炎と抗アクアポリン抗体(神経内科学教室岩田誠教授退任記念特別号)"], "weko_shared_id": 3}