WEKO3
アイテム
膵島移植部位としての小腸漿膜下の有用性
http://hdl.handle.net/10470/25853
http://hdl.handle.net/10470/25853efbb136b-2ed9-4701-99a0-c0eb5052e36a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00006020026.pdf (1.3 MB)
|
|
| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2010-08-10 | |||||||
| タイトル | ||||||||
| タイトル | 膵島移植部位としての小腸漿膜下の有用性 | |||||||
| 言語 | ||||||||
| 言語 | jpn | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 別タイトル | ||||||||
| その他のタイトル | Small Bowel Subserosal Space as a Site for Islet Transplantation | |||||||
| 著者名 |
提嶋, 淳一郎
× 提嶋, 淳一郎
|
|||||||
| 著者別名 | ||||||||
| 識別子Scheme | WEKO | |||||||
| 識別子 | 266254 | |||||||
| 姓名 | SAGESHIMA, Junichiro | |||||||
| 出版者 | ||||||||
| 出版者 | 東京女子医科大学学会 | |||||||
| 受付日付 | ||||||||
| 日付 | 2010-08-10 | |||||||
| 日付タイプ | Created | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0040-9022 | |||||||
| NCID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN00161368 | |||||||
| 書誌情報 |
東京女子医科大学雑誌 巻 71, 号 9/10, p. 691-697, 発行日 2001-10-25 |
|||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | In this study we compared the small bowel subserosal space (SBSS) and a liver omental pouch (LOP) to the classical portal vein (PV) site for islet implantation. Lewis rat islets were isografted into three different transplantation sites in streptozotocin-induced diabetic recipient rats. The SBSS was created by configuring part of the deserosalized jejunum into a U shape whilst the inferior surface of the liver and greater omentum were used to form the LOP. At postoperative day 30, normoglycemia was achieved in 100% (12/12), 80% (8/10), and 50% (5/10) of the PV, SBSS and LOP groups respectively. In successful transplants, the majority of recipients exhibited sustained graft function. Oral glucose tolerance tests revealed that glucose tolerance was comparable in rats with either SBSS or PV islets. Morphologically, many intact islets were evident in the SBSS of normoglycemic recipients, whereas only islets adjacent to the liver surface survived in the LOP group. SBSS is easily accessible for surgical implantation and biopsy and well placed for portal delivery of insulin. In addition, it is capable of local drug delivery. Our results demonstrate that the SBSS is an alternative site for islet transplantation. | |||||||
| 著者所属 | ||||||||
| 東京女子医科大学医学部腎臓外科 | ||||||||
