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造血因子による新しい医療(第25回日本医学会総会プレシンポジウム「先端科学技術と医療」)
http://hdl.handle.net/10470/24693
http://hdl.handle.net/10470/24693f06d4fe1-980b-49b2-b91e-948f71d8e3a7
名前 / ファイル | ライセンス | アクション |
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KJ00006020739.pdf (338.7 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-08-10 | |||||
タイトル | ||||||
タイトル | 造血因子による新しい医療(第25回日本医学会総会プレシンポジウム「先端科学技術と医療」) | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
別タイトル | ||||||
その他のタイトル | Development of New Treatment Using Hematopoietic Growth Factors(The forefront of scientific technique and surgical treatment) | |||||
著者名 |
溝口, 秀昭
× 溝口, 秀昭 |
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著者別名 | ||||||
姓名 | MIZOGUCHI, Hideaki | |||||
出版者 | ||||||
出版者 | 東京女子医科大学学会 | |||||
受付日付 | ||||||
日付 | 2010-08-10 | |||||
日付タイプ | Created | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0040-9022 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00161368 | |||||
書誌情報 |
東京女子医科大学雑誌 巻 69, 号 4, p. 203-207, 発行日 1999-04-25 |
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著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Recent advances in gene technology have revealed the structure of many hematopoietic growth factors and made them available for clinical use. Hematopoietic growth factors induce the differentiation of hematopoiectic stem cells into mature blood cells, such as red blood cells, granulocytes, macrophages and platelets and control the production of these cells. Erythropoietin is a hematopoietic growth factor which stimulates red cell production and is used clinically for the treatment of renal anemia. Measurement of the serum erythropoietin concentration is useful for the diagnosis of erythrocytosis. Concerning granulopoiesis, 3 kinds of colony-stimulating factors (CSF) have been identified. Among them granulocyte CSF (G-CSF) has been used for neutropenia that occurs after chemotherapy for various cancers and after bone marrow transplantation in Japan. Moreover, it has been confirmed that G-CSF mobilizes stem cells into peripheral blood. Therefore, it is possible to collect peripheral stem cells after administration of G-CSF for use in stem cell transplantation. This method is called peripheral stem cell transplantation (PBSCT). Not only autologous PBSCT but also allogeneic PBSCT has been widely performed. Recently thrombopoietin which stimulates platelet production was discovered and its usefulness in the treatment of thrombocytopenia has been proposed. In the future, these hematopoietic growth factors and other hematopoietic growth factors such as stem cell factor and interleukin 3 may be used to expand stem cells for stem cell transplantation and gene transduction for gene therapy. | |||||
著者所属 | ||||||
東京女子医科大学医学部血液内科学 |