ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "bc1b6392-d9a2-441f-b1a2-624da6fe7515"}, "_deposit": {"created_by": 3, "id": "16967", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "16967"}, "status": "published"}, "_oai": {"id": "oai:twinkle.repo.nii.ac.jp:00016967", "sets": ["1927"]}, "author_link": ["261158", "261159", "261160", "261167", "261166", "261163", "261165", "261162", "261164", "261161"], "item_10001_alternative_title_1": {"attribute_name": "別タイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Analysis of the Long-term Effectiveness of Interferon Treatment for Patients with Chronic Hepatitis B"}]}, "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1998-04-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "145", "bibliographicPageStart": "136", "bibliographicVolumeNumber": "68", "bibliographic_titles": [{"bibliographic_title": "東京女子医科大学雑誌"}]}]}, "item_10001_creator_2": {"attribute_name": "著者名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "静間, 徹"}], "nameIdentifiers": [{"nameIdentifier": "261158", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "長谷川, 潔"}], "nameIdentifiers": [{"nameIdentifier": "261159", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "石川, 賀代"}], "nameIdentifiers": [{"nameIdentifier": "261160", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "山内, 克巳"}], "nameIdentifiers": [{"nameIdentifier": "261161", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "林, 直諒"}], "nameIdentifiers": [{"nameIdentifier": "261162", "nameIdentifierScheme": "WEKO"}]}]}, "item_10001_date_25": {"attribute_name": "受付日付", "attribute_value_mlt": [{"subitem_date_issued_datetime": "2010-08-10", "subitem_date_issued_type": "Created"}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Twenty-seven patients with hepatitis B (HB) e-antigen positive chronic hepatitis B were treated with interferon and followed up for 36 to 108 months after cessation of interferon treatment. In 20 (74%) of the patients, HBe-antigen was seroconverted to anti-HBe antibody. Among patients seroconverted from HBe-antigen to anti-HBe antibody, the normalization of serum aminotransferase and disappearance of HBV-DNA from sera occurred in 17 (63%) of the patients. Pre-treatment with steroid and the duration and amount of interferon treatment were unrelated with the effectiveness of the treatment. To study the susceptibility of HB-virus strain with precore mutant to interferon treatment, the sequence at nt. 1986 resulting in a stop codon of the precore region was analyzed by mutation site specific assay (MSSA). The precore sequence was precore mutant strain was as sensitive to interferon as the precore wild type strain. However, from the present findings, viral quantity right after interferon treatment was fairly informative for predicting the long-term outcome.", "subitem_description_type": "Abstract"}]}, "item_10001_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "261163", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "SHIZUMA, Toru"}]}, {"nameIdentifiers": [{"nameIdentifier": "261164", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "HASEGAWA, Kiyoshi"}]}, {"nameIdentifiers": [{"nameIdentifier": "261165", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "ISHIKAWA, Kayo"}]}, {"nameIdentifiers": [{"nameIdentifier": "261166", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "YAMAUCHI, Katsumi"}]}, {"nameIdentifiers": [{"nameIdentifier": "261167", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "HAYASHI, Naoaki"}]}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "東京女子医科大学学会"}]}, "item_10001_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00161368", "subitem_source_identifier_type": "NCID"}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0040-9022", "subitem_source_identifier_type": "ISSN"}]}, "item_10001_text_35": {"attribute_name": "著者所属", "attribute_value_mlt": [{"subitem_text_value": "東京女子医科大学消化器内科学"}, {"subitem_text_value": "東京女子医科大学消化器内科学"}, {"subitem_text_value": "東京女子医科大学消化器内科学"}, {"subitem_text_value": "東京女子医科大学消化器内科学"}, {"subitem_text_value": "東京女子医科大学消化器内科学"}]}, "item_10001_version_type_20": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-03-27"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00006024504.pdf", "filesize": [{"value": "780.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 780200.0, "url": {"label": "KJ00006024504.pdf", "url": "https://twinkle.repo.nii.ac.jp/record/16967/files/KJ00006024504.pdf"}, "version_id": "486eb929-85cf-43e4-8246-2853de309e22"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "B型慢性肝炎に対するインターフェロン療法の長期予後とprecore変異との関連", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "B型慢性肝炎に対するインターフェロン療法の長期予後とprecore変異との関連"}]}, "item_type_id": "10001", "owner": "3", "path": ["1927"], "permalink_uri": "http://hdl.handle.net/10470/24266", "pubdate": {"attribute_name": "公開日", "attribute_value": "2010-08-10"}, "publish_date": "2010-08-10", "publish_status": "0", "recid": "16967", "relation": {}, "relation_version_is_last": true, "title": ["B型慢性肝炎に対するインターフェロン療法の長期予後とprecore変異との関連"], "weko_shared_id": -1}
  1. A 資料種別
  2. 010 東京女子医科大学雑誌
  3. 010A 論文
  4. 68巻
  5. 4号

B型慢性肝炎に対するインターフェロン療法の長期予後とprecore変異との関連

http://hdl.handle.net/10470/24266
http://hdl.handle.net/10470/24266
626fb723-8dba-4701-a98e-d692d028047f
名前 / ファイル ライセンス アクション
KJ00006024504.pdf KJ00006024504.pdf (780.2 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2010-08-10
タイトル
タイトル B型慢性肝炎に対するインターフェロン療法の長期予後とprecore変異との関連
言語
言語 jpn
資源タイプ
資源タイプ journal article
別タイトル
その他のタイトル Analysis of the Long-term Effectiveness of Interferon Treatment for Patients with Chronic Hepatitis B
著者名 静間, 徹

× 静間, 徹

WEKO 261158

静間, 徹

Search repository
長谷川, 潔

× 長谷川, 潔

WEKO 261159

長谷川, 潔

Search repository
石川, 賀代

× 石川, 賀代

WEKO 261160

石川, 賀代

Search repository
山内, 克巳

× 山内, 克巳

WEKO 261161

山内, 克巳

Search repository
林, 直諒

× 林, 直諒

WEKO 261162

林, 直諒

Search repository
著者別名
姓名 SHIZUMA, Toru
著者別名
姓名 HASEGAWA, Kiyoshi
著者別名
姓名 ISHIKAWA, Kayo
著者別名
姓名 YAMAUCHI, Katsumi
著者別名
姓名 HAYASHI, Naoaki
出版者
出版者 東京女子医科大学学会
受付日付
ISSN
収録物識別子タイプ ISSN
収録物識別子 0040-9022
NCID
収録物識別子タイプ NCID
収録物識別子 AN00161368
書誌情報 東京女子医科大学雑誌

巻 68, 号 4, p. 136-145, 発行日 1998-04-25
著者版フラグ
抄録
内容記述タイプ Abstract
内容記述 Twenty-seven patients with hepatitis B (HB) e-antigen positive chronic hepatitis B were treated with interferon and followed up for 36 to 108 months after cessation of interferon treatment. In 20 (74%) of the patients, HBe-antigen was seroconverted to anti-HBe antibody. Among patients seroconverted from HBe-antigen to anti-HBe antibody, the normalization of serum aminotransferase and disappearance of HBV-DNA from sera occurred in 17 (63%) of the patients. Pre-treatment with steroid and the duration and amount of interferon treatment were unrelated with the effectiveness of the treatment. To study the susceptibility of HB-virus strain with precore mutant to interferon treatment, the sequence at nt. 1986 resulting in a stop codon of the precore region was analyzed by mutation site specific assay (MSSA). The precore sequence was precore mutant strain was as sensitive to interferon as the precore wild type strain. However, from the present findings, viral quantity right after interferon treatment was fairly informative for predicting the long-term outcome.
著者所属
東京女子医科大学消化器内科学
著者所属
東京女子医科大学消化器内科学
著者所属
東京女子医科大学消化器内科学
著者所属
東京女子医科大学消化器内科学
著者所属
東京女子医科大学消化器内科学
戻る
0
views
See details
Views

Versions

Ver.1 2023-06-20 22:59:36.452617
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3