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However, the duration from onset of diabetes to puberty was reported to have less influence on the development of retinopathy in young-onset Caucasian IDDM patients. It is uncertain whether this phenomenon is also applicable to young-onset Japanese IDDM patients and if so duration to which age shows less influence on the development of retinopathy. One hundred twenty-three Japanese IDDM patients diagnosed before 25 years of age were recruited for this study in 1983 to investigate the influence of duration and age as the risk factors and determine the critical age at which the influence of duration develops. Subjects had no retinopathy in 1983 and were followed up to the onset of retinopathy or the end of 1993. Statistical analysis of estimates of the duration and metabolic control as the risk factors was performed by Cox\u0027s proportional hazard model. The reuslts are as follows; 1. Metabolic control of diabetes significantly influenced the development of background retinopathy in male and female IDDM patients regardless of age at onset. 2. Duration from onset to 12 years of age had less influence on the development of retinopathy in male IDDM patients. 3. For female IDDM patients, duration to 9 years of age had less influence on the development of retinopathy. 4. A remarkably higher incidence of retinopathy was noted in the female IDDM patients with an age of 9 to 14 years at onset than in the female patients over 14 years of age at onset. 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日本人小児期発症インスリン依存型糖尿病の発症年齢から考察した網膜症出現に関する研究
http://hdl.handle.net/10470/23415
http://hdl.handle.net/10470/23415a25d3fef-691c-43a5-9285-93d2ba64729f
名前 / ファイル | ライセンス | アクション |
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KJ00006025594.pdf (609.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-08-10 | |||||
タイトル | ||||||
タイトル | 日本人小児期発症インスリン依存型糖尿病の発症年齢から考察した網膜症出現に関する研究 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
別タイトル | ||||||
その他のタイトル | Study on Influence of Onset Age of Diabetes on the Development of Background Retinopathy in Young-Onset Japanese IDDM Patients | |||||
著者名 |
樋上, 裕子
× 樋上, 裕子 |
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著者別名 | ||||||
姓名 | HIGAMI, Yuko | |||||
出版者 | ||||||
出版者 | 東京女子医科大学学会 | |||||
受付日付 | ||||||
日付 | 2010-08-10 | |||||
日付タイプ | Created | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0040-9022 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00161368 | |||||
書誌情報 |
東京女子医科大学雑誌 巻 66, 号 5, p. 323-329, 発行日 1996-05-25 |
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著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Duration and degree of metabolic control of diabetes have been known to be major risk factors of the development of diabetic complications, especially diabetic retinopathy. However, the duration from onset of diabetes to puberty was reported to have less influence on the development of retinopathy in young-onset Caucasian IDDM patients. It is uncertain whether this phenomenon is also applicable to young-onset Japanese IDDM patients and if so duration to which age shows less influence on the development of retinopathy. One hundred twenty-three Japanese IDDM patients diagnosed before 25 years of age were recruited for this study in 1983 to investigate the influence of duration and age as the risk factors and determine the critical age at which the influence of duration develops. Subjects had no retinopathy in 1983 and were followed up to the onset of retinopathy or the end of 1993. Statistical analysis of estimates of the duration and metabolic control as the risk factors was performed by Cox's proportional hazard model. The reuslts are as follows; 1. Metabolic control of diabetes significantly influenced the development of background retinopathy in male and female IDDM patients regardless of age at onset. 2. Duration from onset to 12 years of age had less influence on the development of retinopathy in male IDDM patients. 3. For female IDDM patients, duration to 9 years of age had less influence on the development of retinopathy. 4. A remarkably higher incidence of retinopathy was noted in the female IDDM patients with an age of 9 to 14 years at onset than in the female patients over 14 years of age at onset. In conclusion, we suggest that the duration before puberty showed less influence on the development of background retinopathy and the critical age was 12 years for male IDDM patients and 9 years for female IDDM patients. | |||||
著者所属 | ||||||
東京女子医科大学第三内科学教室 |