{"created":"2023-06-20T17:00:54.161688+00:00","id":20451,"links":{},"metadata":{"_buckets":{"deposit":"2d864708-b25c-44af-8541-44f6c401db79"},"_deposit":{"created_by":3,"id":"20451","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"20451"},"status":"published"},"_oai":{"id":"oai:twinkle.repo.nii.ac.jp:00020451","sets":["140:1307:1308:2029:2031"]},"author_link":["298881","298882","298883","298884","298886","298875","298880","298879","298876","298885","298878","298877"],"item_10001_alternative_title_1":{"attribute_name":"別タイトル","attribute_value_mlt":[{"subitem_alternative_title":"Immunoadsorption Plasma Pheresis Therapy for Neuromyelitis Optica(Special Issue in Hornor of the Retirement of Professor Makoto Iwata at the Department of Neurology, Tokyo Women's Medical University)"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-02-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"Extra","bibliographicPageEnd":"E98","bibliographicPageStart":"E94","bibliographicVolumeNumber":"78","bibliographic_titles":[{"bibliographic_title":"東京女子医科大学雑誌"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大橋, 高志"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"太田, 宏平"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"清水, 優子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大原, 久仁子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"竹内, 千仙"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岩田, 誠"}],"nameIdentifiers":[{}]}]},"item_10001_date_25":{"attribute_name":"受付日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-08-10","subitem_date_issued_type":"Created"}]},"item_10001_description_34":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"神経内科学教室岩田誠教授退任記念特別号","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Neuromyelitis optica (NMO) is an idiopathic inflammatory demyelinating disease of the central nervous system characterized by optic neuritis and myelitis. Recently, anti aquaporin-4 antibody, specifically detected in sera from NMO patients, was discovered. The effectiveness of immunoadsorption plasma pheresis (IAPP) therapy for treating acute exacerbations of NMO has not been well evaluated; thus, accumulation of therapeutic experience for this disease is important. We report 3 patients with acute exacerbations of NMO. These patients were unresponsive to intravenous methylprednisolone therapy but showed significant improvement after IAPP therapy. IAPP therapy was well tolerated and effective for a patient with acute exacerbation during pregnancy. We conclude that IAPP therapy is a therapeutic option for patients with a fulminant attack of NMO. It is relatively safe and applicable for patients with acute exacerbation during pregnancy.","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"298881","nameIdentifierScheme":"WEKO"}],"names":[{"name":"OHASHI, Takashi"}]},{"nameIdentifiers":[{"nameIdentifier":"298882","nameIdentifierScheme":"WEKO"}],"names":[{"name":"OTA, Kohei"}]},{"nameIdentifiers":[{"nameIdentifier":"298883","nameIdentifierScheme":"WEKO"}],"names":[{"name":"SHIMIZU, Yuko"}]},{"nameIdentifiers":[{"nameIdentifier":"298884","nameIdentifierScheme":"WEKO"}],"names":[{"name":"OHARA, Kuniko"}]},{"nameIdentifiers":[{"nameIdentifier":"298885","nameIdentifierScheme":"WEKO"}],"names":[{"name":"TAKEUCHI, Chisen"}]},{"nameIdentifiers":[{"nameIdentifier":"298886","nameIdentifierScheme":"WEKO"}],"names":[{"name":"IWATA, Makoto"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東京女子医科大学学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00161368","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0040-9022","subitem_source_identifier_type":"ISSN"}]},"item_10001_subject_47":{"attribute_name":"著者キーワード","attribute_value_mlt":[{"subitem_subject":"neuromyelitis optica","subitem_subject_scheme":"Other"},{"subitem_subject":"immunoadsorption plasma pheresis","subitem_subject_scheme":"Other"},{"subitem_subject":"NMO IgG","subitem_subject_scheme":"Other"},{"subitem_subject":"aquaporin-4","subitem_subject_scheme":"Other"},{"subitem_subject":"pregnancy","subitem_subject_scheme":"Other"}]},"item_10001_text_35":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京女子医科大学医学部神経内科学"},{"subitem_text_value":"東京女子医科大学医学部神経内科学:東京理科大学理学部"},{"subitem_text_value":"東京女子医科大学医学部神経内科学"},{"subitem_text_value":"東京女子医科大学医学部神経内科学"},{"subitem_text_value":"東京女子医科大学医学部神経内科学"},{"subitem_text_value":"東京女子医科大学医学部神経内科学"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-08-22"}],"displaytype":"detail","filename":"KJ00006015121.pdf","filesize":[{"value":"993.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006015121.pdf","url":"https://twinkle.repo.nii.ac.jp/record/20451/files/KJ00006015121.pdf"},"version_id":"e14ffd04-32e9-45e2-99b7-9b1971c3f1a0"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"視神経脊髄炎(NMO)における免疫吸着療法の検討(神経内科学教室岩田誠教授退任記念特別号)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"視神経脊髄炎(NMO)における免疫吸着療法の検討(神経内科学教室岩田誠教授退任記念特別号)"}]},"item_type_id":"10001","owner":"3","path":["2031"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-08-10"},"publish_date":"2010-08-10","publish_status":"0","recid":"20451","relation_version_is_last":true,"title":["視神経脊髄炎(NMO)における免疫吸着療法の検討(神経内科学教室岩田誠教授退任記念特別号)"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T19:57:35.164465+00:00"}