@article{oai:twinkle.repo.nii.ac.jp:00020451,
 author = {大橋, 高志 and 太田, 宏平 and 清水, 優子 and 大原, 久仁子 and 竹内, 千仙 and 岩田, 誠},
 issue = {Extra},
 journal = {東京女子医科大学雑誌},
 month = {Feb},
 note = {神経内科学教室岩田誠教授退任記念特別号, Neuromyelitis optica (NMO) is an idiopathic inflammatory demyelinating disease of the central nervous system characterized by optic neuritis and myelitis. Recently, anti aquaporin-4 antibody, specifically detected in sera from NMO patients, was discovered. The effectiveness of immunoadsorption plasma pheresis (IAPP) therapy for treating acute exacerbations of NMO has not been well evaluated; thus, accumulation of therapeutic experience for this disease is important. We report 3 patients with acute exacerbations of NMO. These patients were unresponsive to intravenous methylprednisolone therapy but showed significant improvement after IAPP therapy. IAPP therapy was well tolerated and effective for a patient with acute exacerbation during pregnancy. We conclude that IAPP therapy is a therapeutic option for patients with a fulminant attack of NMO. It is relatively safe and applicable for patients with acute exacerbation during pregnancy.},
 pages = {E94--E98},
 title = {視神経脊髄炎(NMO)における免疫吸着療法の検討(神経内科学教室岩田誠教授退任記念特別号)},
 volume = {78},
 year = {2008}
}