@article{oai:twinkle.repo.nii.ac.jp:00020415, author = {島崎, 朝子 and 勝部, 隆男 and 肥後, 美和 and 村山, 実 and 五十畑, 則之 and 久原, 浩太郎 and 今野, 宗一 and 塩澤, 俊一 and 吉松, 和彦 and 島川, 武 and 成高, 義彦 and 小川, 健冶 and 相羽, 元彦}, issue = {1}, journal = {東京女子医科大学雑誌}, month = {Jan}, note = {The patient, a woman aged 60, was admitted to this hospital in October 2006 for detailed examinations and treatment because she had developed nausea and a sensation of gastric fullness and was noted to have pyloric stenosis at the time of the checkup. Upper gastrointestinal endoscopy revealed an elevated lesion with regenerative epithelial growth in the prepyloric area (biopsy finding group I). A CT scan of the abdomen showed annular hyperplasia of the pyloric wall, enlargement of the perigastric lymph nodes and multiple metastatic lesions in the liver. A PET-CT scan demonstrated hyperaccumulation in all those lesions. A diagnosis of malignant tumor of the stomach with multiple hepatic metastases and lymph node metastasis was made and a distal gastrectomy with D1+β lymphadenectomy was performed in January 2007. Histopathologic examination revealed cancer cells invading areas ranging from the muscularis propria to the subserosal tissue but there was no evidence of malignant cells in the mucosal epithelium. Chromogranin A stain and synaptophysin stain of the cancer cells were both positive, and a diagnosis of endocrine cell carcinoma was made. The lymph node metastasis and hepatic metastases were also of the same histologic type as the gastric tumor, and the final diagnosis in the case was endocrine cell carcinoma: P0, H1, T2(SS), N2, INFβ, ly0, v3 and Stage IV. The patient is under combination chemotherapy with CDDP and TS-1.}, pages = {18--22}, title = {粘膜下腫瘍の形態を呈した胃内分泌細胞癌の1例}, volume = {78}, year = {2008} }