@article{oai:twinkle.repo.nii.ac.jp:00020239, author = {藤林, 真理子 and 相羽, 元彦 and 澤田, 達男 and 塩澤, 俊一 and 土屋, 玲 and 小川, 健治}, issue = {7}, journal = {東京女子医科大学雑誌}, month = {Jul}, note = {We clinicopathologically examined an adult case of undifferentiated embryonal sarcoma of the liver. A 25-year-old male patient had a large hepatic mass (17cm in the largest dimension) resected. He had recurrent tumors locally and in the pelvic and/or abdominal cavities five times during his course of four years and eight months, and was treated by surgery and chemotherapy. The primary tumor consisted of spindle and cuboidal cells with high nuclear/cytoplasmic ratio, and focally showed a phyllodes tumor-like lesion with hyperplastic bile duct epithelium, in addition to typical histology. Immunohistochemically, it showed only a vimentin positivity. Recurrent tumors exhibited malignant fibrous histiocytoma-like histology with numerous mitoses and atypical mitoses, bizarre nuclei, hyaline globules and a storiform pattern. They showed smooth muscle actin and CD34 immunoreactivity. They were found to invade within abdominal organs at the last surgery. Undifferentiated (embryonal) sarcoma of the liver in adult is extremely rare, and require differential diagnosis. We also discussed the significance of the histology of phylldes tumor-like pattern and sequential histological changes of the tumor.}, pages = {350--357}, title = {成人発症undifferentiated(embryonal)sarcomaの1例}, volume = {77}, year = {2007} }