{"created":"2023-06-20T16:59:17.480879+00:00","id":18335,"links":{},"metadata":{"_buckets":{"deposit":"6d3482e0-f4a3-42df-9933-564221e330da"},"_deposit":{"created_by":3,"id":"18335","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"18335"},"status":"published"},"_oai":{"id":"oai:twinkle.repo.nii.ac.jp:00018335","sets":["140:1307:1308:1956:1959"]},"author_link":["265829","265831","265824","265832","265828","265826","265827","265825","265833","265830"],"item_10001_alternative_title_1":{"attribute_name":"別タイトル","attribute_value_mlt":[{"subitem_alternative_title":"Clinical Characteristics of Prolactinoma During Last Ten Years in the Institute of Clinical Endocrinology, Tokyo Women's Medical University Hospital"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2001-03-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"172","bibliographicPageStart":"166","bibliographicVolumeNumber":"71","bibliographic_titles":[{"bibliographic_title":"東京女子医科大学雑誌"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大森, 就子"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大森, 凡恵"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宇治原, 誠"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"野村, 馨"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高野, 加寿恵"}],"nameIdentifiers":[{}]}]},"item_10001_date_25":{"attribute_name":"受付日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-08-10","subitem_date_issued_type":"Created"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In a retrospective study of the clinical characteristics of prolactinomas in 61 patients treated in the last 10 years, we found that they occurred more of ten in women than in men and at a younger age. Macroadenoma was significantly more prevalent in men at 85%. The fact that women with a disease duration of >12 years had mostly macroadenoma suggests that such a gender-associated difference may be due to the disease duration. To determine the effectiveness of bromocriptine treatment, we measured prolactin (PRL) after a single dose of bromocriptine. When PRL level cutoff became 30% that of controls and success was evaluated by PRL normalization, the bromocriptine test could predict medication success or failure with 83% accuracy. For successful pregnancy, decreased PRL was favorable, but need not necessarily be normal. Medication was more effective in patients with macroadenoma, with normal PRL response to thyrotropin-releasing hormone (TRH), and in men than women, but cured only a few patients. Medication-induced tumor decrease was not notable. Combined surgery and/or radiotherapy was specially useful in macroadenoma patients who failed to enter remission after monotherapy.","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"265829","nameIdentifierScheme":"WEKO"}],"names":[{"name":"OMORI, Nariko"}]},{"nameIdentifiers":[{"nameIdentifier":"265830","nameIdentifierScheme":"WEKO"}],"names":[{"name":"OMORI, Kazue"}]},{"nameIdentifiers":[{"nameIdentifier":"265831","nameIdentifierScheme":"WEKO"}],"names":[{"name":"UJIHARA, Makoto"}]},{"nameIdentifiers":[{"nameIdentifier":"265832","nameIdentifierScheme":"WEKO"}],"names":[{"name":"NOMURA, Kaoru"}]},{"nameIdentifiers":[{"nameIdentifier":"265833","nameIdentifierScheme":"WEKO"}],"names":[{"name":"TAKANO, Kazue"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東京女子医科大学学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00161368","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0040-9022","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_35":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京女子医科大学医学部第二内科学"},{"subitem_text_value":"東京女子医科大学医学部第二内科学"},{"subitem_text_value":"東京女子医科大学医学部第二内科学"},{"subitem_text_value":"東京女子医科大学医学部第二内科学"},{"subitem_text_value":"東京女子医科大学医学部第二内科学"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-03-27"}],"displaytype":"detail","filename":"KJ00006019784.pdf","filesize":[{"value":"502.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006019784.pdf","url":"https://twinkle.repo.nii.ac.jp/record/18335/files/KJ00006019784.pdf"},"version_id":"72d4e4bd-a4c4-45c3-b010-719451551d72"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"東京女子医大病院内分泌センター内科での過去10年間のプロラクチノーマの臨床像","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"東京女子医大病院内分泌センター内科での過去10年間のプロラクチノーマの臨床像"}]},"item_type_id":"10001","owner":"3","path":["1959"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-08-10"},"publish_date":"2010-08-10","publish_status":"0","recid":"18335","relation_version_is_last":true,"title":["東京女子医大病院内分泌センター内科での過去10年間のプロラクチノーマの臨床像"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T22:31:28.725989+00:00"}