{"created":"2023-06-20T16:59:13.289880+00:00","id":18241,"links":{},"metadata":{"_buckets":{"deposit":"b842e968-7c9f-4c58-bd1d-e06aabc8872d"},"_deposit":{"created_by":3,"id":"18241","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"18241"},"status":"published"},"_oai":{"id":"oai:twinkle.repo.nii.ac.jp:00018241","sets":["140:1307:1308:1944:1955"]},"author_link":["265511","265510"],"item_10001_alternative_title_1":{"attribute_name":"別タイトル","attribute_value_mlt":[{"subitem_alternative_title":"Significance of the Infectious Agent in Multiple Sclerosis(Special Issue in Hornor of the Retirement of Professor Toshiko Takemiya at the Department of Neurology, Tokyo Women's Medical University)"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-12-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"E2","bibliographicPageEnd":"E236","bibliographicPageStart":"E230","bibliographicVolumeNumber":"70","bibliographic_titles":[{"bibliographic_title":"東京女子医科大学雑誌"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"太田, 宏平"}],"nameIdentifiers":[{"nameIdentifier":"265510","nameIdentifierScheme":"WEKO"}]}]},"item_10001_date_25":{"attribute_name":"受付日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-08-10","subitem_date_issued_type":"Created"}]},"item_10001_description_34":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"神経内科学教室竹宮敏子教授退任記念特別号","subitem_description_type":"Other"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Multiple sclerosis (MS) is a demyelinating disease of unknown origin. Some kind of infection was thought to disturb the immune regulation in a person susceptible to MS and has also been extensively examined as an influential factor in the etiology of MS. Though the infectious agent including various viruses was mentioned as a candidate, the clear relevance to MS has not been proven. There is the report of endogenous retrovirus, herpes viruses such as EBV and HHV-6, and Chlamydia as infectious agents which may be concerned with the onset of MS after 1990. Ideas such as antigen spreading and molecular mimicry between the protein of microorganisms and myelin antigen have been presented to consider the pathogenesis of MS. Here, I reviewed recent reports on the infectious agent in MS and tried to summarize the relation between the infectious agent and MS.","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"265511","nameIdentifierScheme":"WEKO"}],"names":[{"name":"OTA, Kohei"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東京女子医科大学学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00161368","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0040-9022","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_35":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京女子医科大学医学部脳神経センター神経内科"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-03-27"}],"displaytype":"detail","filename":"KJ00006020610.pdf","filesize":[{"value":"777.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006020610.pdf","url":"https://twinkle.repo.nii.ac.jp/record/18241/files/KJ00006020610.pdf"},"version_id":"c3762c6e-e659-4ebc-be15-576906be0de2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"多発性硬化症における感染因子の意義(神経内科学教室竹宮敏子教授退任記念特別号)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"多発性硬化症における感染因子の意義(神経内科学教室竹宮敏子教授退任記念特別号)"}]},"item_type_id":"10001","owner":"3","path":["1955"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-08-10"},"publish_date":"2010-08-10","publish_status":"0","recid":"18241","relation_version_is_last":true,"title":["多発性硬化症における感染因子の意義(神経内科学教室竹宮敏子教授退任記念特別号)"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T19:55:02.142228+00:00"}