{"created":"2023-06-20T16:59:12.105048+00:00","id":18214,"links":{},"metadata":{"_buckets":{"deposit":"d239cfc1-e6a5-4a9a-9fdf-32bef560f5ed"},"_deposit":{"created_by":3,"id":"18214","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"18214"},"status":"published"},"_oai":{"id":"oai:twinkle.repo.nii.ac.jp:00018214","sets":["140:1307:1308:1944:1954"]},"author_link":["265359","265360","265356","265358","265361","265364","265357","265365","265362","265363"],"item_10001_alternative_title_1":{"attribute_name":"別タイトル","attribute_value_mlt":[{"subitem_alternative_title":"Application of New Antithrombogenic Polymer with Microdomain Surfaces to a Small Caliber Vascular Prosthesis"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-12-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"12","bibliographicPageEnd":"811","bibliographicPageStart":"801","bibliographicVolumeNumber":"70","bibliographic_titles":[{"bibliographic_title":"東京女子医科大学雑誌"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"舘林, 孝幸"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"毛井, 純一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"銭, 勇"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岡野, 光夫"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"新田, 澄郎"}],"nameIdentifiers":[{}]}]},"item_10001_date_25":{"attribute_name":"受付日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-08-10","subitem_date_issued_type":"Created"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"2-Hydroxyethyl methacrylate and styrene block copolymer (HEMA-St) has been reported to show excellent blood compatibility in both in vivo and in vitro experiments. HEMA-St suppresses platelet adhesion and activation. The poor elastomeric properties of HEMA-St, however, have been an obstacle to application in small caliber vascular prostheses. We have developed a new amphiphilic block copolymer composed of HEMA and octyistyrene (HEMA-Octst) that improves the mechanical properties of HEMA-St. A small caliber vascular graft has now been fabricated using HEMA-Octst. The graft consists of a trilayered structure with Dacron composing the outer layer, polyurethane for the middle layer, and a HEMA-Octst coating for the inner layer. Three grafts were used in canine coronary artery bypass procedures to evaluate the grafts. Two of the grafts used in the coronary artery bypass were patent after 8～15 days. The HEMA-Octst coating did not show any surface cracks when examined using a scanning electron microscope, and the new grafts was sutured in place with 7-0 polypropylene sutures. HEMA-Octst has improved elastomeric properties and excellent blood compatibility. The material appears to be highly promising for applications in small caliber vascular prostheses that do not require an endothelial cell lining.","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"265361","nameIdentifierScheme":"WEKO"}],"names":[{"name":"TATEBAYASHI, Takayuki"}]},{"nameIdentifiers":[{"nameIdentifier":"265362","nameIdentifierScheme":"WEKO"}],"names":[{"name":"KEI, Junichi"}]},{"nameIdentifiers":[{"nameIdentifier":"265363","nameIdentifierScheme":"WEKO"}],"names":[{"name":"QIAN, Yong"}]},{"nameIdentifiers":[{"nameIdentifier":"265364","nameIdentifierScheme":"WEKO"}],"names":[{"name":"OKANO, Teruo"}]},{"nameIdentifiers":[{"nameIdentifier":"265365","nameIdentifierScheme":"WEKO"}],"names":[{"name":"NITTA, Sumio"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東京女子医科大学学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00161368","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0040-9022","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_35":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京女子医科大学医学部第一外科学"},{"subitem_text_value":"東京女子医科大学医学部第一外科学"},{"subitem_text_value":"東京女子医科大学医学部第一外科学"},{"subitem_text_value":"東京女子医科大学医用工学研究施設"},{"subitem_text_value":"東京女子医科大学医学部第一外科学"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-03-27"}],"displaytype":"detail","filename":"KJ00006020583.pdf","filesize":[{"value":"2.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006020583.pdf","url":"https://twinkle.repo.nii.ac.jp/record/18214/files/KJ00006020583.pdf"},"version_id":"75434749-2b86-4753-9b61-428e765a5a1f"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ミクロ相分離構造を有する抗血栓材料コーティング小口径人工血管の実験的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ミクロ相分離構造を有する抗血栓材料コーティング小口径人工血管の実験的研究"}]},"item_type_id":"10001","owner":"3","path":["1954"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-08-10"},"publish_date":"2010-08-10","publish_status":"0","recid":"18214","relation_version_is_last":true,"title":["ミクロ相分離構造を有する抗血栓材料コーティング小口径人工血管の実験的研究"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T22:33:01.890773+00:00"}