@article{oai:twinkle.repo.nii.ac.jp:00017914,
 author = {宇治原, 誠 and 野村, 馨 and 岡本, 高宏},
 issue = {6/7},
 journal = {東京女子医科大学雑誌},
 month = {Jul},
 note = {A study protocol is presented as an example to establish evidence with high validity, entitled as, "Randomized controlled trial (RCT) of levothyroxine suppressive therapy for benign, solid thyroid nodules and multinodular goiter". RCT has to be carefully planned and performed to overcome a variety of biases, confounders, and also ethical problems, in order to establish strong evidence. In this paper, we report several problems we encountered in our study with a hope to be helpful for a researcher who plans to do RCT.},
 pages = {321--326},
 title = {Evidence-Based Medicine (EBM)入門ガイド(6) : 臨床試験の試み-甲状腺結節,Multinodular Goiterに対するレボチロキシン治療のRandomized Controlled Tria1の試み-},
 volume = {70},
 year = {2000}
}