{"created":"2023-06-20T16:58:39.218242+00:00","id":17476,"links":{},"metadata":{"_buckets":{"deposit":"93006fe9-f52f-4fbe-8067-d35140633033"},"_deposit":{"created_by":3,"id":"17476","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"17476"},"status":"published"},"_oai":{"id":"oai:twinkle.repo.nii.ac.jp:00017476","sets":["140:1307:1308:1934:1939"]},"author_link":["262673","262684","262680","262676","262683","262682","262674","262679","262678","262681","262677","262675"],"item_10001_alternative_title_1":{"attribute_name":"別タイトル","attribute_value_mlt":[{"subitem_alternative_title":"神経性食欲不振症に誤診された視床下部腫瘍の男性例"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-06-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"295","bibliographicPageStart":"289","bibliographicVolumeNumber":"69","bibliographic_titles":[{"bibliographic_title":"東京女子医科大学雑誌"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"HOTTA, Mari"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SHIBASAKI, Tamotsu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SATO, Kanji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KUBO, Osami"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"DEMURA, Hiroshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKANO, Kazue"}],"nameIdentifiers":[{}]}]},"item_10001_date_25":{"attribute_name":"受付日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-08-10","subitem_date_issued_type":"Created"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"20歳の男性で,食欲不振,体重減少,自己嘔吐などの行動異常,病識のなさ,精神症状および人格の変化から最初の医療機関で神経性食欲不振症と誤って診断された.その後,複数の医療機関を受診したが,本人の精神および行動異常から十分な内科的検査がされず,全身状態の悪化と意識障害で当科に緊急入院した.胚細胞腫と考えられる視床下部腫瘍で,それによる下垂体機能低下症と尿崩症と診断された.患者は多飲多尿を申告せず,副腎皮質ホルモンの低下によって経過中に多尿は改善していたことが判明し,視床下部腫瘍による口渇感の喪失が明らかになった.Chipkevitchによる今まで報告された神経性食欲不振症に酷似した視床下部腫瘍21例の再検討では,やせをきたす身体疾患がないという項目以外の診断基準を完全に満たすものは2例であったが,行動および人格異常は,視床下部腫瘍による神経症状の出現に平均2.9年先行して出現しており,注意深い経過観察が必要なことを報告している.神経性食欲不振症患者数は増加しており,女子高校生や大学生の1%と推測されている.男性例も稀ではなくなり,全患者の1～5%で,当科でも1.3%である.しかし,本症の診断には器質的疾患の鑑別は非常に重要である.下垂体機能低下症と異なり,神経性食欲不振症では,血漿成長ホルモン,ACTH,コルチゾールが高値となることが多く,鑑別に有用である.","subitem_description_type":"Abstract"},{"subitem_description":"A 20-year-old Japanese man with a hypothalamic tumor which caused hypopituitarism and diabetes insipidus was mistakenly diagnosed as anorexia nervosa because of anorexia, weight loss, denial of being ill, changes in personality, and abnormal behavior resembling the clinical characteristics of anorexia nervosa. After irradiation therapy, he gained weight and is behaving normally under replacement therapy. Unlike in hypopituitarism, anorexia nervosa patients often have elevated plasma levels of growth hormone (GH), cortisol or adrenocorticotropin (ACTH). Careful testing and examination must be performed to distinguish between anorexia nervosa and other organic disorders.","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"262679","nameIdentifierScheme":"WEKO"}],"names":[{"name":"堀田, 眞理"}]},{"nameIdentifiers":[{"nameIdentifier":"262680","nameIdentifierScheme":"WEKO"}],"names":[{"name":"芝崎, 保"}]},{"nameIdentifiers":[{"nameIdentifier":"262681","nameIdentifierScheme":"WEKO"}],"names":[{"name":"佐藤, 幹二"}]},{"nameIdentifiers":[{"nameIdentifier":"262682","nameIdentifierScheme":"WEKO"}],"names":[{"name":"久保, 長生"}]},{"nameIdentifiers":[{"nameIdentifier":"262683","nameIdentifierScheme":"WEKO"}],"names":[{"name":"出村, 博"}]},{"nameIdentifiers":[{"nameIdentifier":"262684","nameIdentifierScheme":"WEKO"}],"names":[{"name":"高野, 加寿恵"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東京女子医科大学学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00161368","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0040-9022","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_35":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women s Medical University, School of Medicine"},{"subitem_text_value":"The Department of Physiology, Nippon Medical School"},{"subitem_text_value":"Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women s Medical University, School of Medicine"},{"subitem_text_value":"Department of Neurosurgery, Neurological Institute, Tokyo Women s Medical University, School of Medicine"},{"subitem_text_value":"Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women s Medical University, School of Medicine"},{"subitem_text_value":"Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women s Medical University, School of Medicine"},{"subitem_text_value":"東京女子医科大学内分泌疾患総合医療センター内科"},{"subitem_text_value":"日本医科大学生理学"},{"subitem_text_value":"東京女子医科大学内分泌疾患総合医療センター内科"},{"subitem_text_value":"東京女子医科大学脳神経センター外科"},{"subitem_text_value":"東京女子医科大学内分泌疾患総合医療センター内科"},{"subitem_text_value":"東京女子医科大学内分泌疾患総合医療センター内科"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-03-27"}],"displaytype":"detail","filename":"KJ00006020753.pdf","filesize":[{"value":"745.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006020753.pdf","url":"https://twinkle.repo.nii.ac.jp/record/17476/files/KJ00006020753.pdf"},"version_id":"1e32ab97-c52f-4245-8250-82007163ee2a"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A Young Male with a Hypothalamic Tumor Mimicking Anorexia Nervosa","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A Young Male with a Hypothalamic Tumor Mimicking Anorexia Nervosa"}]},"item_type_id":"10001","owner":"3","path":["1939"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-08-10"},"publish_date":"2010-08-10","publish_status":"0","recid":"17476","relation_version_is_last":true,"title":["A Young Male with a Hypothalamic Tumor Mimicking Anorexia Nervosa"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T22:48:41.202592+00:00"}