{"created":"2023-06-20T16:58:15.262117+00:00","id":16933,"links":{},"metadata":{"_buckets":{"deposit":"1b55925a-00b6-4d93-b432-5d9ac3533e3b"},"_deposit":{"created_by":3,"id":"16933","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"16933"},"status":"published"},"_oai":{"id":"oai:twinkle.repo.nii.ac.jp:00016933","sets":["140:1307:1308:1924:1926"]},"author_link":["261037","261033","261036","261032","261035","261034","261030","261031"],"item_10001_alternative_title_1":{"attribute_name":"別タイトル","attribute_value_mlt":[{"subitem_alternative_title":"Clinical and Hormonal Characteristics of Non-functioning Adrenal Incidentaloma"}]},"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-03-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"65","bibliographicPageStart":"57","bibliographicVolumeNumber":"68","bibliographic_titles":[{"bibliographic_title":"東京女子医科大学雑誌"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"片山, 真由美"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"野村, 馨"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宇治原, 誠"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"出村, 博"}],"nameIdentifiers":[{}]}]},"item_10001_date_25":{"attribute_name":"受付日付","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-08-10","subitem_date_issued_type":"Created"}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"CT or MRI scan has revealed unexpected adrenal masses during examinations for unrelated disease with the frequency ranging from 0.4 to 1.3%. Most of these incidentalomas were adenomas that had lost the ability to secrete biological potent hormones, i.e., nonfunctioning adenoma. The present study was to clarify the clinical characteristics and steroidogenesis of these incidentalomas. The frequency of adrenal incidentaloma on CT scan examined in 1,116 subjects in a general hospital increased after age 60, i.e., 0.49% between 40 and 49 years, 0.43% between 50 and 59 years, 0.87% between 60 and 69 years, and 0.82% between 70 and 79 years. Forty-four patients have been diagnosed to have a nonfunctioning adenoma(s) in our department. They were frequently suffered from hypertension, impaired glucose intolerance, and/or hyper-lipidemia. These findings suggest that nonfunctioning adenomas may be an aging-related phenomenon. Nonfunctioning adenomas were small and grew very slowly. No difference in frequency was seen between men and women. Rapid ACTH tests was conducted in 8 patients with nonfunctioning adenoma. Plasma 17-hydroxyprogesterone (17-OHP) increased excessively in one patient and increased fairly in two. A hyperresponder of 17-OHP in rapid ACTH test was thus present, although its frequency was lower than that reported in Caucasians. Thus, the impairment of steroidogenesis at or proximal to 21-hydroxylation may occur in most of non-functioning adenomas.","subitem_description_type":"Abstract"}]},"item_10001_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"261034","nameIdentifierScheme":"WEKO"}],"names":[{"name":"KATAYAMA, Mayumi"}]},{"nameIdentifiers":[{"nameIdentifier":"261035","nameIdentifierScheme":"WEKO"}],"names":[{"name":"NOMURA, Kaoru"}]},{"nameIdentifiers":[{"nameIdentifier":"261036","nameIdentifierScheme":"WEKO"}],"names":[{"name":"UJIHARA, Makoto"}]},{"nameIdentifiers":[{"nameIdentifier":"261037","nameIdentifierScheme":"WEKO"}],"names":[{"name":"DEMURA, Hiroshi"}]}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東京女子医科大学学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00161368","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0040-9022","subitem_source_identifier_type":"ISSN"}]},"item_10001_text_35":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"東京女子医科大学第二内科学教室"},{"subitem_text_value":"東京女子医科大学第二内科学教室"},{"subitem_text_value":"東京女子医科大学第二内科学教室"},{"subitem_text_value":"東京女子医科大学第二内科学教室"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-03-27"}],"displaytype":"detail","filename":"KJ00006024462.pdf","filesize":[{"value":"820.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00006024462.pdf","url":"https://twinkle.repo.nii.ac.jp/record/16933/files/KJ00006024462.pdf"},"version_id":"cf9f2705-c6c4-4e02-9ed9-1530f035c8bd"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"非機能性副腎偶発腫瘍の臨床像とステロイド生合成系に関する検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"非機能性副腎偶発腫瘍の臨床像とステロイド生合成系に関する検討"}]},"item_type_id":"10001","owner":"3","path":["1926"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-08-10"},"publish_date":"2010-08-10","publish_status":"0","recid":"16933","relation_version_is_last":true,"title":["非機能性副腎偶発腫瘍の臨床像とステロイド生合成系に関する検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T23:00:23.411682+00:00"}