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非弁膜症性心房細動における血栓塞栓症の臨床的および凝血学的研究
http://hdl.handle.net/10470/23696
http://hdl.handle.net/10470/23696dce19c03-6287-43a2-843f-03e89cafde19
名前 / ファイル | ライセンス | アクション |
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KJ00006025929.pdf (861.2 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-08-10 | |||||
タイトル | ||||||
タイトル | 非弁膜症性心房細動における血栓塞栓症の臨床的および凝血学的研究 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
別タイトル | ||||||
その他のタイトル | Clinical and Hemostatic Studies in Nonvalvular Atrial Fibrillation | |||||
著者名 |
薄井, 秀美
× 薄井, 秀美 |
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著者別名 | ||||||
姓名 | USUI, Hidemi | |||||
出版者 | ||||||
出版者 | 東京女子医科大学学会 | |||||
受付日付 | ||||||
日付 | 2010-08-10 | |||||
日付タイプ | Created | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0040-9022 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00161368 | |||||
書誌情報 |
東京女子医科大学雑誌 巻 66, 号 12, p. 1063-1072, 発行日 1996-12-25 |
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著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | It is generally accepted that atrial fibrillation (Af) is associated with an increased risk of thromboembolism, especially in valvular Af. In recent years, several major studies have established that patients with nonvalvular atrial fibrillation (NVAf) are at increased risk of thromboembolism. I studied whether clinical and coagulation factors contribute to an increased risk of thromboembolism in NVAf. In 518 patients with NVAf (361 males and 157 females), 279 patients had heart disease and 239 patients were lone Af. Seventy four (14%) patients had prior thromboembolism. The left atrial diameter was larger in patients with prior thromboembolism than in those without it. During a mean follow-up of 8.5 months, the rate of primary embolic event in patients with NVAf was 2.7% per year. Various coagulation and fibrinolysis markers were assayed in 73 patients with NVAf. Thrombin-antithrombin III complex (TAT) levels increased in 22 patients (30%) and D-dimer levels increased in 11 patients (15%). TAT and D-dimer levels decreased after warfarin therapy in patients with their increases. In this study, it was suggested that NVAf increased the risk of thromboembolism and warfarin was effective for prevention of thromboembolism in NVAf. | |||||
著者所属 | ||||||
東京女子医科大学循環器内科学教室 |